The Vivabrain project is an interdisciplinary project, involving medecine, applied mathematic and computer science laboratories. It is funded by the ANR, the french agency of research.
The project aims at providing tools to analyze complex cerebral angiographic data, in order to help doctors in understanding cerebrovascular issues and eventually guide them in their analysis. The purpose of this project is to develop a pipeline for the generation of virtual Magnetic Resonance Angiographies (MRA) of the human brain, associated to their anatomical (3D) and hemodynamic (3D+t) models (providing a ground-truth)
The project needs to consider the following issues:
- The handling of inter-individual cerebrovascular variability, in the context of anatomical model generation.
- The numeric simulation of blood flows in complex geometries and in multiphysic and multiscale frameworks.
- The accurate simulation of the physical processes involved in MRA acquisition sequences in order to finally obtain realistic virtual angiographic images.
In order to do so, the successive steps are considered:
- Extraction of vascular volumes from real MRA images.
- Generation of 3D vascular models from these data.
- 3D+t simulation of blood flow in complex (arterial and venous) models.
Simulation of MR acquisition of angiographic data from these 3D+t models.
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